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The use of Human Growth Hormone or HGH for energy and endurance is controversial and hotly debated. Though it is approved for use in the treatment of a limited number of medical conditions, the FDA stipulates that it is illegal to distribute HGH products for anti-aging, bodybuilding, or athletic enhancement.

What It Is

HGH is a natural peptide hormone that plays a crucial role in the manufacture and repair of cell tissue.

Where It Comes From

The body produces HGH in the pituitary gland. Normally healthy people produce sufficient HGH but it is believed that the body's ability to manufacture HGH declines with age.

For many decades HGH for medical treatment was only available as extracted from cadavers, which necessarily limited its use. However several forms of HGH are currently available. It can be produced through recombinant DNA technology, and since 1985 biosynthetic forms of HGH have been approved for use. In addition, there are a number of products on the market branded as HGH "releasers", substances which theoretically stimulate the body's production of the hormone.

What It Does

The primary function of HGH is the stimulation of growth and cell reproduction, regeneration, and repair. It promotes protein synthesis, increases muscle mass, and stimulates the growth of internal organs. HGH is also known to increase calcium retention, which has a positive impact on bone strength, and to enhance immune system function.

HGH supplements are used to treat conditions that result in short stature, growth failure, and delayed sexual maturity. These conditions include chronic renal failure, Turner Syndrome, and a deficiency of the hormone itself. It is also an accepted and clinically-proven treatment in building and maintaining muscle mass due to wasting diseases such as AIDS and Prader-Willi syndrome.

Research on the use of HGH for a variety of other conditions, including multiple sclerosis, obesity, fibromyalgia, heart disease, colitis, and Chron's disease is ongoing. It is also viewed by some as a potential anti-aging agent. Though some studies have shown encouraging potential, the results remain inconclusive and the use of the hormone for non-growth-related conditions is controversial.

For almost 40 years HGH has been used to improve athletic performance in many sports. However its use is banned as doping by many organizations, including the IOC and the NCAA.

How It Works To Enhance Energy and Endurance

• HGH produces an anabolic or building effect on body tissues, including muscle tissue and internal organs. HGH proponents say that this can effectively increase strength, flexibility, endurance, and tissue resilience in healthy individuals.
• HGH is considered by many to be an important anti-aging tool because of its ability to repair and regenerate tissue. Research on the use of HGH in elderly men has indicated that groups taking HGH supplements showed a halt in age-related loss of bone density and a clinically significant increase in muscle mass. Additional benefits from HGH, including increased energy, endurance, and sexual function, have also been reported but remain clinically undocumented.

Dosage, Dangers, Contraindications, And Side Effects

There are a number of potential dangers and side effects from excess amounts of HGH, including pituitary atrophy, tumors, and acromegaly (thickening and enlargement of bones in the jaw and fingers). Joint pain and swelling, sleep problems, and an increased risk of diabetes have also been associated with HGH usage.

HGH should not be used by diabetics, pregnant or lactating women, cancer patients, or children whose bone growth has not completed.

You can also read about Vitamin D supplements for depression at Take This, You'll Feel Better.

Are You Still Struggling to Control Acne & Wishing You Could Remove Acne Scars Forever?

Skin Infection and Marks: Not a Problem; for a living creature who needs to protect his nude and very moist skin from opportunistic bacteria, pollution and hazards. And HOW! So much so that it created THE SOLUTION, naturally! FOR YOU TOO!

Acne infection may seem an inescapable curse of adolescence. But a natural solution may spare your skin from such annoying vicissitude altogether.

Acne vulgaris. It's an unkind-sounding term for a genuinely unwelcome skin problem: acne breakouts that disturb teens, adults and haunts them when it leaves behind horrid scars.

Technically they are the result of inflammation in the sebum canals and the proliferation, inside clogged pores, of acne bacteria that normally live in symbiosis and balance with us humans. Yes they create sebum for the lubrication of the surface of our skin and its protection from other micro-organisms. But the friendly symbiosis holds only until those bacteria get uncontrolled when disturbed by a feat of excessive sebum production, triggered by hormonal upswings during puberty, as their flow outside is blocked and sebum accumulates within the sebum canals. The latter because the sebum canal is pinched-off by pressure from denatured and hydrated cooked proteins that we have ingested and have become toxins deposited inside the dermis by our lymphatic system, as it lacks the ability to dispose of them through the kidneys, liver and digestive system.

While these phenomena does disturbingly affect adults too, it positively takes up residence on the beautiful faces of those entering the blossoming years of puberty.

While many people can manage to keep acne under control with over the counter products made with harsh chemicals they are mostly unaware that those chemicals have long term damaging effects on their skin, or do not care much, as long as the chemicals destroy the acne bacteria and let them live with fewer pimples and zits. At least that may be true for a while. Unfortunately it is more likely that acne breakouts will return over and over again.

Nevertheless, it is most desirable to get rid of them with something more gentle, natural and without the long term side effects, or to be able to skip them in the first place. Is it not?

No one likes the way those breakouts look not even if they're a telltale sign of an adolescent's growth. Significant energy has been invested to discover how to prevent or get rid of acne breakouts and the scars, red or dark pigmentation they leave behind, with less than satisfactory results. Until recently.

The key lays in new understandings in the biochemistry of how the human body maintains health at the cellular level. Those bring forth by carbohydrate science, a new frontier in knowledge also known as the sweet science of glycobiology. The term glyco stands for the sugar component made of carbon, hydrogen and oxygen of complex macromolecules that bind to proteins and are essential nutrients and structural elements of the dermis, the middle layer of the skin, right below the surface.

Most of our cells are studded with those sticky, sugary molecules. The role of carbohydrates (sugars) in energy production has been long understood. However, their additional, crucial role in orchestrating the healthy structure and function of the body is a relatively new discovery of glycobiology, and reveals their importance in treating underlying causes of problems in the skin (such as acne) and other organs.

The major organic components of human cells, those that contain carbon atoms, are proteins, lipids, carbohydrates and carbohydrate-containing molecules, and the nucleic acids (DNA and RNA). The molecules in which carbohydrates are attached to proteins or lipids are called glycoconjugates and are quite complex. The skin matrix is rich in these complex sugars.

Skin matrix is a framework that holds the skin together and consists mainly of intermeshed polymers such as collagen and elastin plus glycoconjugates. The skin matrix is responsible for the skin's mechanical properties, including firmness, strength, suppleness, and elasticity.

There are three major classes of glycoconjugates: glycoproteins, proteoglycans, and glycolipids. The first two are proteins bound to carbohydrate or glyco chains, the latter are lipids bound to glycomolecules. They are all ubiquitous components of the extra cellular matrix, a complex structure composed of many types of macromolecules which interact with connective tissue cells to maintain tissue integrity and functionality.

These molecules have a large water holding capacity -true moisturizing- and provide support and skin strength.

Advances in skin biology have identified these molecules as also essential for processes such as wound healing, tumor formation, inflammation, skin infection, oxidation, photo aging, thinning, sagging, lack of strength and tensile force as is the case in stretch marks. Thus, a glyconutrient approach gets at the root cause and underlying skin regeneration, defense from microbial pathogens, and repair processes rather than treating only the symptoms.

The skin is positioned at the interface between an organism's internal milieu and an external environment characterized by constant assault with potential microbial pathogens. While the skin was formerly considered an inactive physical protective barrier that participates in host immune defense merely by blocking entry of microbial pathogens, it is now apparent that a major role of the skin is to defend the body by rapidly mounting an innate immune response to injury and microbial insult. In the skin, both resident and infiltrating cells synthesize and secrete small peptides that have a broad-spectrum antimicrobial activity against bacteria, fungi, and viruses. Antimicrobial peptides also act as immune effectors by stimulating cytokine and chemokine production, angiogenesis, and wound healing.

Recently 3 antimicrobial peptides: the cathelicidins, defensins, and dermcidins have been shown to act by directly inhibiting pathogen growth as well as potentiating other branches of the innate, humoral, and cell-mediated immune system.

Antimicrobial peptides are effector molecules of the innate immune system. Human antimicrobial peptides bind to glycosaminoglycans. And the obverse, structural motifs associated with glycosaminoglycans confer antimicrobial properties to certain peptides.

Instead of fighting the symptoms of skin inflammation and an impaired ability of defending oneself from uncontrolled infection the stimulation of endogenous synthesis of glycosaminoglycans and proteoglycans seems to be a more sound strategy and sure way to prevent and recover from acne skin infections.

The good news is that this can be done topically -that is by applying a product on the skin- more so than by a nutritional approach rich on those glyconutrients, which is nevertheless good advice. May we suggest you do a little research about them, for then it may also lead you to avoid eating too much cooked proteins.

Topical application has the advantage that it gets to the target cells directly as nowadays this is possible with current technology. It is achieved by encapsulating the highly water-soluble glyconutrients in tiny microscopic fat vessels or tiny oil droplets called liposomes, making it highly penetrable directly through the skin into the target areas. This transports more glyconutrients directly to the skin areas where it is most needed.

The most natural, complete and balanced source of the complex glycoconjugates required to keep skin healthy is a substance produced by a tiny creature as a fluid that bubbles onto its exposed skin to keep it supple, able to stretch and snap back, and healthy; while also triggering its repair and regeneration when damaged.

This substance is the natural mucous fluid secreted by garden snails. This secretion as is naturally, not some molecules isolated from it (and used as a drug), is now made into a natural skin care cream.

The cream, as all remedies, only works if you use it consistently, preferably twice a day if you are already affected by pimples. And for at least three weeks before you'll notice a significant difference. Of course, given that the process is easy and leaves your skin feeling soft and supple, being assiduous shouldn't be a problem.

About the Author

Martha Fitzharris, writing about Nature's Gift for Healthy Skin. Cream to Abate Acne Scars, and Clear Acne & Rosacea, and shrink Keloid Scars, Hypertrophic Scars, Prevent and Treat Stretch Marks

Biotage extends peptide synthesis research collaboration with University of Copenhagen
Biotage, a leading supplier of tools and technology for medicinal and analytical chemistry, announced an agreement to extend the research collaboration with Professor Knud J. Jensen at the Faculty of Life Sciences, University of Copenhagen, to develop new applications on the Biotage Syro Wave in the field of synthetic peptide and protein chemistry. The collaboration builds on Professor Jensen's ...

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